Most football offenses have an I formation, but this can be run out of any 2 back set.
This play works best after running your 3 hole lead several times. The key is the tight end needs to chip (hit the defensive tackle) as he releases into his route. This will freeze the linebacker over him and allow the X and Z receivers to catch the attention of the FS and SS.
The QB fakes the hand off on the lead. The first back through the hole continues out into the left flat and will be the secondary receiver. The deep back will come up into the hole after the play fake and block. The (Y) tight end will be open for a big play.
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